New combo therapy shows promise for tough lung cancers

NCT ID NCT04701307

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 28 times

Summary

This study tests two drugs—niraparib and dostarlimab—together in people with small cell lung cancer or other high-grade neuroendocrine cancers that have already been treated. Niraparib blocks a repair process in cancer cells, while dostarlimab helps the immune system attack them. The goal is to see if this combination can slow or stop the cancer from growing. About 48 adults are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.