Electric fields and drug combo shows promise for deadly brain tumor

NCT ID NCT04221503

First seen Jan 11, 2026 · Last updated May 16, 2026 · Updated 16 times

Summary

This study tests a combination of a drug called niraparib and a device that delivers low-intensity electric fields (Tumor-Treating Fields) in 30 adults whose glioblastoma brain tumor has come back after radiation. The goal is to see if this treatment can shrink or stabilize the tumor. Participants must have a measurable tumor on MRI and known MGMT methylation status. The study is not expected to cure the disease but aims to control it.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.