Glowing dye reveals hidden clues in rheumatoid arthritis

NCT ID NCT05197530

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a special dye and camera to look at lymph vessels in the hands of people with rheumatoid arthritis. The dye is injected into the skin and glows under a near-infrared camera, allowing researchers to see how lymph fluid moves. The goal is to better understand how the disease progresses and how treatments might work. The study involves 40 adults with early or late rheumatoid arthritis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Indocyanine green (a dye injected into the skin to make lymph vessels glow under a special camera)

What this could lead to

If successful, this imaging method could help doctors track rheumatoid arthritis progression and see how well treatments are working.

What could go wrong

This is a very early, small pilot study (40 people). It is testing a method, not a treatment, so it won't directly improve symptoms. The dye may cause rare allergic reactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Rochester

    RECRUITING

    Rochester, New York, 14642, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••