Glowing dye reveals hidden clues in rheumatoid arthritis

NCT ID NCT05197530

Recruiting now Knowledge-focused Sponsor: University of Rochester Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a special dye and camera to look at lymph vessels in the hands of people with rheumatoid arthritis. The dye is injected into the skin and glows under a near-infrared camera, allowing researchers to see how lymph fluid moves. The goal is to better understand how the disease progresses and how treatments might work. The study involves 40 adults with early or late rheumatoid arthritis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Indocyanine green (a dye injected into the skin to make lymph vessels glow under a special camera)
What this could lead to: If successful, this imaging method could help doctors track rheumatoid arthritis progression and see how well treatments are working.
What could go wrong: This is a very early, small pilot study (40 people). It is testing a method, not a treatment, so it won't directly improve symptoms. The dye may cause rare allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for RHEUMATOID ARTHRITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RHEUMATOID ARTHRITIS

Contacts and locations

Locations

University of Rochester
RECRUITING

Rochester, New York, 14642, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.