New gum surgery aims to save teeth from advanced periodontitis
NCT ID NCT03997578
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new surgical technique called NIPSA, combined with a gum graft and special proteins, to treat severe gum disease. Forty adults with periodontitis and deep gum pockets will receive the procedure. The goal is to see if this approach can reduce pocket depth and improve gum attachment better than standard treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
connective tissue graft plus enamel matrix derivative and xenograft
What this could lead to
If successful, this could offer a more effective surgical option to repair gum and bone damage from periodontitis, potentially saving teeth that might otherwise be lost.
What could go wrong
This is a small, early-phase trial with only 40 participants, so results may not apply to everyone. Surgery carries risks like infection, pain, or graft failure, and long-term benefits are not yet proven.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centro Odontologico Del Sureste Slp
RECRUITINGMurcia, 30007, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••