Donor nipple graft offers new hope for breast cancer reconstruction

NCT ID NCT04534010

Terminated Disease control Sponsor: Stanford University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested a new type of nipple reconstruction using a graft made from donated human nipples. Six breast cancer survivors who had already undergone breast reconstruction surgery received the graft. The goal was to see if the graft was safe and how long it took to heal, as well as how satisfied patients were with the results.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: decellularized human nipple-areola complex graft
What this could lead to: If successful, this could offer a more natural option for nipple reconstruction after breast cancer, improving appearance and self-esteem.
What could go wrong: This was a very small pilot study (6 participants) that was terminated early, so results are limited. The graft may not heal properly or could have complications like infection or poor cosmetic outcome.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Locations

Stanford University

Stanford, California, 94304, United States

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