New device could help measure pain in tiniest babies

NCT ID NCT05223790

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested a device called NIPE that measures heart rate changes to detect pain in very premature babies (born before 34 weeks) who are sedated and on ventilators. Researchers compared NIPE readings before and during care procedures in 50 infants. The goal was to see if this monitor can reliably assess pain and discomfort in this vulnerable group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a better way to measure pain in premature babies who cannot speak, helping doctors adjust care more precisely.

What could go wrong

This is a small, early study with only 50 babies. The NIPE monitor may not prove reliable enough for routine use, and results may not apply to all preterm infants.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hop Jeanne de Flandre Chu Lille

    Lille, 59037, France