Promising new drug cocktail targets tough pancreatic cancer

NCT ID NCT07277452

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether adding nimotuzumab, a targeted antibody, to standard chemotherapy can help people with high-risk pancreatic cancer that can still be surgically removed. About 156 participants will receive either the drug combo or a placebo before and after surgery. The main goal is to see if it delays cancer recurrence.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Nimotuzumab (a targeted antibody) combined with nab-paclitaxel and gemcitabine (chemotherapy)
What this could lead to
If it works, this could offer a more effective treatment option for people with high-risk pancreatic cancer, potentially delaying recurrence and extending survival.
What could go wrong
This is an early phase 2 trial with only 156 participants. The drug may not improve outcomes over standard care, and side effects from the combination could be significant.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Chunyi Hao

    Beijing, 100000, China

  • Kuirong Jiang

    Nanjing, Jiangsu, 210029, China

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