Former NFL players join brain study to uncover concussion effects

NCT ID NCT04263337

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 250 former NFL players and healthy volunteers aged 50-70 over 5 years. Researchers use brain scans, blood tests, and thinking/memory assessments to understand how concussions and repeated head impacts affect long-term brain health. The goal is to gather information that could lead to future treatments, but no experimental therapy is given.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help identify early signs of brain problems in former NFL players and guide future treatments.

What could go wrong

This is an observational study, not a treatment trial. It may not lead directly to any new therapies, and results may not apply to all athletes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CONCUSSION, BRAIN are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Brain Concussion Neurologic Manifestations traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston Children's Hospital

    Waltham, Massachusetts, 02453, United States

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, 27599, United States