Radiation-Free hope: new combo shows promise for rectal cancer

NCT ID NCT07127497

First seen Nov 21, 2025 · Last updated May 25, 2026 · Updated 24 times

Summary

This study tests whether a combination of chemotherapy and an immunotherapy drug (sintilimab) can effectively treat locally advanced rectal cancer without using radiation. The goal is to shrink or eliminate the tumor before surgery, potentially allowing patients to avoid radiation side effects and preserve organ function. The trial involves 50 adults with a specific type of rectal cancer that has not spread widely.

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Contacts and locations

Locations

  • The First Affiliated Hospital of Anhui Medical University

    Hefei, Anhui, 230022, China

Conditions

Explore the condition pages connected to this study.