New combo therapy aims to wipe out rectal cancer before surgery

NCT ID NCT07478731

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding the drug SHR-1701 to standard chemoradiotherapy can completely eliminate tumors in people with advanced rectal cancer before they have surgery. About 48 adults aged 18-75 with a specific type of rectal cancer will receive the treatment over several cycles, followed by tumor removal. The main goal is to see if no cancer cells remain after treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal carcinoma colorectal neoplasm rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tongji Medical College, Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, 430000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••