New hope for kids with tough cancers: Two-Drug attack enters trial

NCT ID NCT06465199

Summary

This study is testing a new oral drug, AMXT 1501, combined with an existing drug called DFMO, for children and young adults with aggressive cancers that have come back or didn't respond to standard treatments. The first part aims to find a safe dose, and the second part will compare the two-drug combo to DFMO alone to see which is better at keeping cancer from growing. It includes patients up to age 21 with specific cancers like neuroblastoma, certain brain tumors, and bone cancers.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Arkansas Children's Hospital

    RECRUITING

    Little Rock, Arkansas, 72202, United States

    Contact

    Contact Email: •••••@•••••

  • Children's Medical Center

    RECRUITING

    Dallas, Texas, 75235, United States

    Contact Email: •••••@•••••

    Contact

  • Connecticut Children's Hospital

    RECRUITING

    Hartford, Connecticut, 06106, United States

    Contact Email: •••••@•••••

    Contact

  • Kapiolani Medical Center for Women and Children

    RECRUITING

    Honolulu, Hawaii, 96813, United States

    Contact Email: •••••@•••••

    Contact

  • Penn State Milton S. Hershey Medical Center and Children's Hospital

    RECRUITING

    Hershey, Pennsylvania, 17033, United States

    Contact Email: •••••@•••••

    Contact

  • St. Joseph's Children's Hospital

    RECRUITING

    Tampa, Florida, 33614, United States

    Contact

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.