Promising 4-Drug cocktail targets multiple myeloma early

NCT ID NCT04430894

First seen Jan 31, 2026 · Last updated Apr 28, 2026 · Updated 9 times

Summary

This study tests a combination of four drugs (carfilzomib, lenalidomide, dexamethasone, and isatuximab) in 50 adults with newly diagnosed multiple myeloma who are eligible for a stem cell transplant. The goal is to see how many patients achieve a complete response after four treatment cycles. While the approach aims to control the disease effectively, patients may still need ongoing therapy, so it is not a cure.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.