New cocktail of drugs shows promise for Tough-to-Treat colorectal cancer

NCT ID NCT06967155

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 27 times

Summary

This study is testing a combination of four drugs (irinotecan, dabrafenib, trametinib, and either cetuximab or panitumumab) as a second treatment option for people with advanced colorectal cancer that has spread and has a specific BRAF gene mutation. The goal is to see if this mix can shrink tumors or slow the disease. About 23 adults are taking part, and the study will track their progress for up to 3 years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Blokhin's Russian Cancer Research Center

    Moscow, Moscow, 115478, Russia

Conditions

Explore the condition pages connected to this study.