New Two-Drug attack targets Tough-to-Treat cancers

NCT ID NCT06157892

Recruiting now Disease control Sponsor: Seagen, a wholly owned subsidiary of Pfizer Source: ClinicalTrials.gov ↗

Summary

This study is testing a new combination of two cancer drugs, disitamab vedotin and tucatinib, for people with advanced or spreading breast or stomach cancer. The main goals are to find a safe and effective dose and to see if the combination can shrink tumors. It is for people whose cancer has a specific marker called HER2 and has continued to grow despite standard treatments.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

A.O.U. Federico II
RECRUITING

Naples, Campania, 80131, Italy
A.O.U. Federico II- U.O.C. Diagnostica per lmmagini e Radioterapia
RECRUITING

Naples, 80131, Italy
Atlanta Cancer Care - Atlanta
RECRUITING

Atlanta, Georgia, 30342, United States
Atlanta Cancer Care - Cumming
RECRUITING

Cumming, Georgia, 30041, United States
Azienda Ospedaliera Universitaria (AOU) Federico II
RECRUITING

Naples, Campania, 80131, Italy
Azienda Ospedaliera Universitaria Integrata di Verona.
RECRUITING

Verona, Veneto, 37134, Italy
BC Cancer Kelowna.
RECRUITING

Kelowna, British Columbia, V1Y 5L3, Canada
Banner-University Medical Center Tucson Campus
RECRUITING

Tucson, Arizona, 85704, United States
Banner-University Medical Center Tucson Campus
RECRUITING

Tucson, Arizona, 85719, United States
Barnes-Jewish Hospital
RECRUITING

St Louis, Missouri, 63110, United States
Brigham and Women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States
CETIR Grup Medic
RECRUITING

Barcelona, 08950, Spain
Cancer Institute Hospital of JFCR
NOT_YET_RECRUITING

Koto-ku, Tokyo, 135-8550, Japan
Carbone Cancer Center / University of Wisconsin
RECRUITING

Madison, Wisconsin, 53792, United States
Chang Gung Medical Foundation Linkou Chang Gung Memorial Hospital
NOT_YET_RECRUITING

Taoyuan District, 333, Taiwan
Charité Universitätsmedizin Berlin, Campus Benjamin Franklin (CBF)
RECRUITING

Berlin, 12203, Germany
Chungbuk National University Hospital
NOT_YET_RECRUITING

Cheongju-si, 28644, South Korea
Colorado West Healthcare System, dba Community Hospital
RECRUITING

Grand Junction, Colorado, 81505, United States
Colorado West Healthcare, dba Grand Valley Oncology
RECRUITING

Grand Junction, Colorado, 81505, United States
Dana Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States
Dana Farber Cancer Institute- Chestnut Hill
RECRUITING

Newton, Massachusetts, 02459, United States
Danbury Hospital
RECRUITING

Danbury, Connecticut, 06810, United States
Dong-A University Hospital
NOT_YET_RECRUITING

Busan, Other, 49201, South Korea
Ecg Medica Sl
RECRUITING

Valencia, 46004, Spain
Farmacia-Ensayos. Planta S - Hospital Universitario HM Sanchinarro-CIOCC-START Madrid
RECRUITING

Madrid, 28050, Spain
Fred Hutchinson Cancer Center / Seattle Cancer Care Alliance / University of Washington
RECRUITING

Seattle, Washington, 98109, United States
Gachon University Gil Medical Center
NOT_YET_RECRUITING

Incheon, 21565, South Korea
Georgetown University Medical Center
RECRUITING

Washington D.C., District of Columbia, 20007, United States
Georgia Cancer Specialists - Annex
RECRUITING

Atlanta, Georgia, 30341, United States
Georgia Cancer Specialists - Athens
RECRUITING

Athens, Georgia, 30606, United States
Georgia Cancer Specialists - Blairsville
RECRUITING

Blairsville, Georgia, 30512, United States
Georgia Cancer Specialists - Canton
RECRUITING

Canton, Georgia, 30115, United States
Georgia Cancer Specialists - Cumming
RECRUITING

Cumming, Georgia, 30041, United States
Georgia Cancer Specialists - Decatur
RECRUITING

Decatur, Georgia, 30033, United States
Georgia Cancer Specialists - Macon
RECRUITING

Macon, Georgia, 31217, United States
Georgia Cancer Specialists - Marietta
RECRUITING

Marietta, Georgia, 30060, United States
Georgia Cancer Specialists-Northside
RECRUITING

Atlanta, Georgia, 30342, United States
Grupo Hospitalario QuironSalud
RECRUITING

Erandio Bizkaia, 48950, Spain
H. Lee Moffitt Cancer Center and Research Institute
RECRUITING

Tampa, Florida, 33612, United States
Harborview Medical Center
RECRUITING

Seattle, Washington, 98104, United States
Heidelberg University Hospital and German Cancer Research Center
RECRUITING

Heidelberg, 69120, Germany
Hospital Clinico Universitario de Valencia
RECRUITING

Valencia, 46010, Spain
Hospital Universitari Vall d´Hebron
RECRUITING

Barcelona, 08035, Spain
Hospital Universitario de Basurto
RECRUITING

Bilbao, 48013, Spain
Humanitas Istituto Clinico Catanese
RECRUITING

Misterbianco (CT), Sicily, 95045, Italy
Institut Catala d'Oncologia
RECRUITING

Barcelona, 08908, Spain
Investigational Drug Service
RECRUITING

Long Island City, New York, 11101, United States
Istituto Europeo di Oncologia
RECRUITING

Milan, Lombardy, 20141, Italy
Istituto Nazionale Tumori IRCCS Fondazione G. Pascale.
NOT_YET_RECRUITING

Naples, Campania, 80131, Italy
Japanese Foundation for Cancer Research
NOT_YET_RECRUITING

Koto-ku, Tokyo, 135-8550, Japan
Korea University Anam Hospital
RECRUITING

Seoul, 02841, South Korea
Linkou Chang Gung Memorial Hospital
NOT_YET_RECRUITING

Taoyuan, 333, Taiwan
MSK Basking Ridge
RECRUITING

Basking Ridge, New Jersey, 07920, United States
MSK Bergen.
RECRUITING

Montvale, New Jersey, 07645, United States
MSK Commack.
RECRUITING

Commack, New York, 11725, United States
MSK Monmouth.
RECRUITING

Middletown, New Jersey, 07748, United States
MSK Nassau.
RECRUITING

Uniondale, New York, 11553, United States
MSK Westchester.
RECRUITING

Harrison, New York, 10604, United States
Massachusetts General Hospital.
RECRUITING

Boston, Massachusetts, 02114, United States
MedStar Georgetown University Hospital
RECRUITING

Washington D.C., District of Columbia, 20007, United States
Memorial Hospital
RECRUITING

Shiloh, Illinois, 62269, United States
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States
Memorial Sloan Kettering Cancer Center - Main Hospital
RECRUITING

New York, New York, 10065, United States
Moffitt Cancer Center - International Plaza
RECRUITING

Tampa, Florida, 33607, United States
Moffitt Cancer Center - McKinley Campus
RECRUITING

Tampa, Florida, 33612, United States
Moffitt Cancer Center at Wesley Chapel
RECRUITING

Wesley Chapel, Florida, 33544, United States
Moffitt McKinley Hospital
RECRUITING

Tampa, Florida, 33612, United States
National Cancer Center
RECRUITING

Goyang-si, Other, 10408, South Korea
National Cheng Kung University Hospital
NOT_YET_RECRUITING

Tainan, 704017, Taiwan
National Cheng Kung University Hospital
NOT_YET_RECRUITING

Tainan, 704, Taiwan
National Taiwan University Cancer Center
NOT_YET_RECRUITING

Taipei, 106, Taiwan
National Taiwan University Hospital
NOT_YET_RECRUITING

Taipei, 100225, Taiwan
National Taiwan University Hospital
NOT_YET_RECRUITING

Taipei, 100, Taiwan
Niguarda Ca' Granda Hospital
RECRUITING

Milan, Lombardy, 20162, Italy
Northside Hospital
RECRUITING

Atlanta, Georgia, 30342, United States
Northside Hospital, Inc.- Central Research Department
RECRUITING

Atlanta, Georgia, 30342, United States
Okayama University Hospital
NOT_YET_RECRUITING

Okayama, 700-8558, Japan
Ottawa Hospital Cancer Centre
RECRUITING

Ottawa, Ontario, K1H 8L6, Canada
Parkland Health and Hospital System
RECRUITING

Dallas, Texas, 75235, United States
Peninsula & South Eastern Hematology and Oncology Group (PASO)
NOT_YET_RECRUITING

Frankston, Victoria, 3199, Australia
Peninsula & South Eastern Hematology and Oncology Group (PASO)
NOT_YET_RECRUITING

Frankston, Australia
Peter MacCallum Cancer Centre
NOT_YET_RECRUITING

Melbourne, 3000, Australia
Quirén Salud Barcelona
RECRUITING

Barcelona, 08023, Spain
Renown Regional Medical Center
RECRUITING

Reno, Nevada, 89502, United States
SCRI Oncology Partners
RECRUITING

Nashville, Tennessee, 37203, United States
START Madrid-CIOCC_Hospital HM Sanchinarro
RECRUITING

Madrid, 28050, Spain
Saint Francis Hospital / Bon Secours - South Carolina
RECRUITING

Greenville, South Carolina, 29607, United States
Saint Luke's Cancer Institute LLC
RECRUITING

Kansas City, Missouri, 64111, United States
Saint Luke's Hospital Investigational Pharmacy
RECRUITING

Kansas City, Missouri, 64111, United States
San Juan Oncology Associates
TERMINATED

Farmington, New Mexico, 87401, United States
Sarah Cannon Research Institute - Pharmacy
RECRUITING

Nashville, Tennessee, 37203, United States
Seoul National University Bundang Hospital
RECRUITING

Seongnam-si, Gyeonggi-do, 13620, South Korea
Seoul National University Hospital
RECRUITING

Seoul, Seoul-teukbyeolsi [seoul], 03080, South Korea
Severance Hospital Yonsei University Health System
RECRUITING

Seoul, 03722, South Korea
Showa University Hospital
NOT_YET_RECRUITING

Shinagawa-ku, Tokyo-to, 142-8666, Japan
Siteman Cancer Center - North County
RECRUITING

Florissant, Missouri, 63031, United States
Siteman Cancer Center - Shiloh
RECRUITING

Shiloh, Illinois, 62269, United States
Siteman Cancer Center - South County
RECRUITING

St Louis, Missouri, 63129, United States
Siteman Cancer Center - St Peters
RECRUITING

City of Saint Peters, Missouri, 63376, United States
Siteman Cancer Center - West County
RECRUITING

Creve Coeur, Missouri, 63141, United States
Slade Health
NOT_YET_RECRUITING

Mount Waverley, Victoria, 3149, Australia
Slade Pharmacy Frankston
NOT_YET_RECRUITING

Frankston, Victoria, 3199, Australia
St Bartholomew's Hospital
NOT_YET_RECRUITING

London, EC1M 6BQ, United Kingdom
St. Vincent's Hospital, The Catholic University of Korea
NOT_YET_RECRUITING

Suwon, 16247, South Korea
Suburban Hematology-Oncology Associates - Duluth
RECRUITING

Duluth, Georgia, 30096, United States
Suburban Hematology-Oncology Associates- Lawrenceville
RECRUITING

Lawrenceville, Georgia, 30046, United States
Sunnybrook Health Sciences Centre
RECRUITING

Toronto, Ontario, M4N 3M5, Canada
Tennessee Oncology-Nashville/Sarah Cannon Research Institute
RECRUITING

Nashville, Tennessee, 37203, United States
The Christie NHS Foundation Trust
NOT_YET_RECRUITING

Manchester, M20 4GJ, United Kingdom
The Royal Marsden Hospital
RECRUITING

Sutton, Surrey, SM2 5PT, United Kingdom
The Royal Marsden Hospital
RECRUITING

London, SW3 6JJ, United Kingdom
The Royal Marsden NHS Foundation Trust
RECRUITING

Sutton, Surrey, SM2 5PT, United Kingdom
The Royal Marsden NHS Foundation Trust
RECRUITING

London, SW3 6JJ, United Kingdom
The Royal Marsden NHS Foundation Trust
RECRUITING

Sutton, SM2 5PT, United Kingdom
The Royal Marsden NHS Foundation Trust (RM)
RECRUITING

London, SW3 6JJ, United Kingdom
The University of Arizona Cancer Center-Main
RECRUITING

Tucson, Arizona, 85724, United States
The University of Arizona Cancer Center-North Campus Pharmacy, Attn: Kelly Myrdal
RECRUITING

Tucson, Arizona, 85719, United States
The Whittingham Cancer Center / Norwalk Hospital
RECRUITING

Norwalk, Connecticut, 06856, United States
UC Irvine Health - Chao Family Comprehensive Cancer Center
RECRUITING

Orange, California, 92868, United States
UC Irvine Medical Center
RECRUITING

Orange, California, 92868, United States
UCLA Department of Medicine - Hematology & Oncology
RECRUITING

Santa Monica, California, 90404, United States
UCLA Hematology/Oncology - Parkside
RECRUITING

Santa Monica, California, 90404, United States
Universitatsklinikum Essen
RECRUITING

Essen, 45147, Germany
University Health Network - Princess Margaret Cancer Centre
RECRUITING

Toronto, Ontario, M5G 2M9, Canada
University of Arizona Cancer Center - North Campus
RECRUITING

Tucson, Arizona, 85719, United States
University of California, San Francisco | HDFCCC - Hematopoietic Malignancies
RECRUITING

San Francisco, California, 94158, United States
University of Texas Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States
University of Texas Southwestern Medical Center - Simmons Cancer Center
RECRUITING

Dallas, Texas, 75235, United States
University of Texas Southwestern Medical Center Clinical Lab-Zale Lipshy University Hospital
RECRUITING

Dallas, Texas, 75390, United States
University of Texas Southwestern Medical Center Simmons Cancer Center - Redbird
RECRUITING

Dallas, Texas, 75237, United States
University of Texas Southwestern Medical Center Simmons Cancer Center - Richardson/Plano
RECRUITING

Richardson, Texas, 75080, United States
University of Texas Southwestern Medical Center-Simmons Cancer Center Pharmacy
RECRUITING

Dallas, Texas, 75235, United States
University of Texas Southwestern Medical Center-William P. Clements Jr. University Hospital
RECRUITING

Dallas, Texas, 75390, United States
University of Texas Southwestern Simmons Cancer Center - Fort Worth
RECRUITING

Fort Worth, Texas, 76104, United States
University of Washington Medical Center
RECRUITING

Seattle, Washington, 98195, United States
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
RECRUITING

Madison, Wisconsin, 53718, United States
Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63110, United States
Washington University School of Medicine - Siteman Cancer Center
RECRUITING

St Louis, Missouri, 63110, United States
Zangmeister Cancer Center
RECRUITING

Columbus, Ohio, 43219, United States

Conditions

Explore the condition pages connected to this study.

ADVANCED BREAST CANCER ADVANCED GASTRIC CANCER BREAST NEOPLASMS GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA HER2 LOW BREAST NEOPLASMS HER2 POSITIVE BREAST NEOPLASMS METASTATIC BREAST CANCER METASTATIC GASTRIC CANCER STOMACH NEOPLASMS TRIPLE NEGATIVE BREAST NEOPLASMS