Two-Pronged immune attack tested against standard care in advanced stomach cancer fight

NCT ID NCT06346197

Summary

This study is testing whether a new combination of two immunotherapy drugs (botensilimab + balstilimab) works better than the current standard treatment for people with advanced stomach, esophageal, or gastro-esophageal junction cancers that have specific genetic features (MSI-H/dMMR). The trial will enroll 132 adults who have not yet received treatment for their advanced cancer. Participants will be randomly assigned to receive either the new two-drug immunotherapy or the standard treatment, which combines chemotherapy with a different immunotherapy drug (nivolumab).

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Brest

    RECRUITING

    Brest, 29000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU de Poitiers

    RECRUITING

    Poitiers, 86000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Léon Bérard

    RECRUITING

    Lyon, 69008, France

    Contact Email: •••••@•••••

  • Hôpital Privé Jean Mermoz

    RECRUITING

    Lyon, 69008, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Paoli Calmettes

    RECRUITING

    Marseille, 13000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.