First patients test new 'Smart Bomb' drug for advanced cancers

NCT ID NCT05216432

Recruiting now Disease control Sponsor: Relay Therapeutics, Inc. Source: ClinicalTrials.gov ↗

Summary

This is the first study in people to test a new drug called RLY-2608, which is designed to target a specific genetic mutation (PIK3CA) found in many advanced solid tumors and breast cancers. The main goals are to find the safest and most effective dose, check for side effects, and see if the drug can help control cancer growth. The drug will be tested alone and in combination with other standard breast cancer medications.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Boca Raton Clinical Research (BRCR) Global
WITHDRAWN

Plantation, Florida, 33322, United States
Centre Léon Bérard
RECRUITING

Lyon, Auvergne-Rhône-Alpes, 69008, France
Columbia University Herbert Irving Comprehensive Cancer Center
RECRUITING

New York, New York, 10032, United States
Community Health Network
RECRUITING

Indianapolis, Indiana, 46250, United States
Dana-Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States
Florida Cancer Specialists
RECRUITING

Orlando, Florida, 32827, United States
Gustave Roussy
RECRUITING

Villejuif, 94805, France
HealthONE
RECRUITING

Denver, Colorado, 80218, United States
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Inova Schar Cancer Center
RECRUITING

Fairfax, Virginia, 22031, United States
Institut Catala D'Oncologia - Badalona (ICO Badalona)
RECRUITING

Barcelona, 08916, Spain
Institute Bergonié
RECRUITING

Bordeaux, 33076, France
Instituto Valenciano de Oncologia
RECRUITING

Valencia, Valencia, 46009, Spain
Istituto Europeo di Oncologia IRCCS
RECRUITING

Milan, 20141, Italy
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
Memorial Sloan Kettering
RECRUITING

New York, New York, 10065, United States
NEXT Virginia
RECRUITING

Fairfax, Virginia, 22301, United States
NYU Langone
RECRUITING

New York, New York, 10016, United States
Peter MacCallum Cancer Center
RECRUITING

Melbourne, Victoria, 3000, Australia
Renown Regional Medical Center
RECRUITING

Reno, Nevada, 89502, United States
Rutgers University
RECRUITING

New Brunswick, New Jersey, 08901, United States
START Barcelona
RECRUITING

Barcelona, Catalonia, 08023, Spain
START Madrid - Hospital Fundacion Jimenez Diaz
RECRUITING

Madrid, 28040, Spain
St Vincents Hospital
RECRUITING

Sydney, New South Wales, 2019, Australia
Tennessee Oncology
RECRUITING

Nashville, Tennessee, 37203, United States
The Alfred Hospital
RECRUITING

Melbourne, Victoria, 3004, Australia
The University of Arizona Cancer Center
RECRUITING

Tucson, Arizona, 85724, United States
The University of Texas M.D. Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
UW Carbone Cancer Center
RECRUITING

Madison, Wisconsin, 53792, United States
University of California-San Diego
RECRUITING

San Diego, California, 90293, United States
University of Chicago Medical Center
RECRUITING

Chicago, Illinois, 60637, United States
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Texas Southwestern Medical Center
RECRUITING

Dallas, Texas, 75235, United States
University of Utah- Huntsman Cancer Center
RECRUITING

Salt Lake City, Utah, 84112, United States
Vall d'Hebron Instituto de Oncologia
RECRUITING

Barcelona, Barcelona, 08035, Spain
Washington University School of Medicine St. Louis
RECRUITING

St Louis, Missouri, 63110, United States
Yale University
RECRUITING

New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.

ADVANCED BREAST CANCER BREAST CANCER HER2-NEGATIVE BREAST CANCER METASTATIC BREAST CANCER PIK3CA MUTATION SOLID TUMOR, ADULT UNRESECTABLE SOLID TUMOR