Could removing a mole help treat vitiligo? new trial aims to find out
NCT ID NCT07307534
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether surgically removing the central mole (halo nevus) in people with vitiligo leads to better skin color restoration than using medication alone. Sixty participants aged 6 to 45 will be randomly assigned to either have the mole removed plus standard treatment, or receive only standard treatment. The trial will track repigmentation over 6 months to see which approach works better.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Central nevus excision (surgery or laser) plus standard medication (tacrolimus ointment and NB-UVB phototherapy, with possible oral prednisone)
What this could lead to
If successful, this could show that removing the central nevus improves repigmentation in vitiligo patients with halo nevi, offering a better treatment approach.
What could go wrong
This is a small, early-stage trial with only 60 participants, so results may not apply to everyone. Surgery carries risks like scarring or infection, and the benefit over medication alone is not yet proven.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Xijing Hospital
Xi'an, Shaanxi, 710032, China
Contact Phone: •••-•••-•••• Email: •••••@•••••