Zapping a nerve in the ear may shield cancer patients' hearts from chemo damage

NCT ID NCT05921253

Recruiting now Disease control Sponsor: University of Oklahoma Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tests if a mild electrical pulse to a nerve in the ear (vagus nerve) can help protect the heart in people receiving strong chemotherapy for breast cancer or lymphoma. About 104 adults who recently started chemo and have extra heart risks will be randomly assigned to get the nerve stimulation or a fake version. The goal is to see if this simple, non-invasive method can improve heart function and reduce inflammation.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER LYMPHOMA

Contacts and locations

Locations

Stephenson Cancer Center
RECRUITING

Oklahoma City, Oklahoma, 73104, United States
Stephenson Cancer Center- Tulsa
NOT_YET_RECRUITING

Tulsa, Oklahoma, 74104, United States

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