Can stem cells rebuild the brain after stroke?

NCT ID NCT04631406

Ongoing ⭐️ CURE ⭐️ Sponsor: Clarion Cells, Inc. Source: ClinicalTrials.gov ↗

First seen Aug 11, 2026 · Last updated Aug 13, 2026 · Updated 2 times

Summary

This trial tests whether transplanting neural stem cells directly into the brain can help people who have had a chronic ischemic stroke. The study involves adults aged 18-75 who had a stroke 6 to 60 months prior. Participants receive a single dose of stem cells, and the trial evaluates safety and potential improvements in motor function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Neural stem cells (NR1) derived from human embryonic stem cells, injected directly into the brain
What this could lead to: If successful, this could lead to a new treatment that repairs brain damage and improves motor function after a stroke.
What could go wrong: This is an early-stage trial with a small number of participants, so safety and effectiveness are not yet proven. There are risks from the surgical procedure and the need for immunosuppression.

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Conditions

The condition(s) this trial relates to.

ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ISCHEMIC STROKE

Contacts and locations

Locations

Stanford Health Center

Stanford, California, 94305, United States

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