New device zaps kidney nerves to tame stubborn high blood pressure

NCT ID NCT07273877

ENROLLING_BY_INVITATION Disease control Sponsor: Shanghai Golden Leaf MedTec Co. Ltd Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a device that uses radiofrequency energy to calm overactive kidney nerves, which can drive high blood pressure. It includes 1,000 people whose blood pressure stays high despite taking three or more medications, or who can't tolerate those drugs. Researchers will track blood pressure changes over time to see if the procedure is safe and effective in real-world settings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Netrod-RDN renal artery radiofrequency ablation system (a device that uses heat to calm kidney nerves)
What this could lead to: If it works, this could offer a new option for people with hard-to-control high blood pressure, potentially reducing their need for multiple medications.
What could go wrong: This is an observational study, not a controlled trial, so results may be less reliable. The procedure involves risks like damage to the kidney artery or nerve injury.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder resistant hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTENSION

Contacts and locations

Locations

Capital Medical University Beijing Anzhen Hospital

Beijing, Beijing Municipality, China

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