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Eye drops aim to boost blood flow in glaucoma suspects

NCT ID NCT04401982

Recruiting now Knowledge-focused Sponsor: University of Maryland, Baltimore Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study compares two eye drop treatments—latanoprost alone versus a combination of netarsudil and latanoprost (Rocklatan)—to see if the combination improves blood flow in the veins around the eye. Researchers will use special imaging techniques to measure blood flow in adults with ocular hypertension or suspected glaucoma. The goal is to understand whether adding netarsudil can increase blood flow beyond what latanoprost does alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Rocklatan (netarsudil/latanoprost) and latanoprost
What this could lead to
If successful, this could show that netarsudil improves eye blood flow, potentially leading to better treatments for glaucoma.
What could go wrong
This is a small, early-phase study focused on measuring blood flow, not on long-term outcomes. The results may not translate to better vision or disease control.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ocular hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OCULAR HYPERTENSION SUSPECT GLAUCOMA

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Maryland Eye Consultants and Surgeons

    RECRUITING

    Silver Spring, Maryland, 20902, United States

  • UM Faculty Physicians, Inc. | 5900 Waterloo Crossing

    RECRUITING

    Columbia, Maryland, 21045, United States

  • University Physicians Inc.

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact Email: •••••@•••••

  • University of Maryland Medical Center

    RECRUITING

    Baltimore, Maryland, 21201, United States

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