New device aims to curb opioid withdrawal without drugs

NCT ID NCT04916600

Ongoing Symptom relief Sponsor: Wayne State University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a device called NET that uses mild electrical stimulation to reduce opioid withdrawal symptoms. It involves 108 adults who want to stop using opioids without taking other medications. Participants are randomly assigned to get real or sham device treatment, and researchers measure withdrawal severity and abstinence over 12 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: NET device (a non-invasive electrical stimulation device)
What this could lead to: If it works, this could offer a drug-free way to manage opioid withdrawal symptoms, helping people achieve abstinence without medication.
What could go wrong: This is an early-stage study with only 108 participants, and it compares the device to a sham (fake) device. The device may not work better than placebo, and long-term effectiveness is unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID-USE DISORDER

Contacts and locations

Locations

Isaiah House Treatment Center

Willisburg, Kentucky, 40078, United States

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