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Nerve block vs local shots: which eases pain after Weight-Loss surgery?

NCT ID NCT07816055

Symptom relief Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 11, 2026 · Last updated Sep 11, 2026

Summary

Researchers compare two ways to control pain after laparoscopic sleeve gastrectomy, a weight-loss operation. One method injects a local anesthetic around the surgical port sites. The other uses ultrasound to guide a nerve block that numbs a wider area of the upper belly. The trial measures opioid use and pain scores in the first 24 hours after surgery to see which approach works better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine, a local anesthetic, given either as an ultrasound-guided external oblique intercostal nerve block or as injections around the surgical port sites
What this could lead to
If the nerve block works better, it could become a standard way to control pain after weight-loss surgery and reduce the need for opioid painkillers.
What could go wrong
This is a small, single-center study. The nerve block may not work better than the simpler injections, and it requires ultrasound guidance and more training to perform.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 54 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * • Age 18-65 years * BMI between 35 kg/m2 and 40 kg/m² * ASA (I-II-III) * Elective laparoscopic sleeve gastrectomy * Ability to provide informed consent Exclusion Criteria: * • Patient refusal * Allergy to local anesthetics * Coagulopathy * Infection at injection site * Chronic opioid use * Hepatic failure * Renal failure * Conversion to open surgery * OSAS-home CPAP * Cardiac patients * Super morbid \>50 kg / m²

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Conditions

The condition(s) this trial relates to.

obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Laparoscopic sleeve gastrectomy

How to take part

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  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

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  2. A doctor treating you

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