Nerve block before face surgery may cut opioid need
NCT ID NCT06429501
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a numbing injection (nerve block) given before facial fracture surgery can lower the amount of opioids patients need after surgery. 70 adults with facial fractures will be randomly assigned to receive either the nerve block or a placebo. The goal is to see if the nerve block reduces opioid use and related side effects like nausea.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bupivacaine with epinephrine
What this could lead to
If it works, this could offer a way to manage pain after facial surgery with fewer opioids and less nausea.
What could go wrong
This is a small, early-phase trial. The nerve block may not reduce opioid use significantly, and results may not apply to all patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Washington University
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••