New nerve block could cut opioid use after gallbladder removal

NCT ID NCT07332546

Completed Symptom relief Sponsor: Shiyou Wei Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 08, 2026 · Updated 3 times

Summary

This study tests whether a specific nerve block, called an external oblique intercostal block, can reduce pain and the need for opioid painkillers after laparoscopic gallbladder removal. Fifty-six adults scheduled for this surgery will be randomly assigned to receive either the nerve block or standard care. The main goal is to see if the block lowers opioid use in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: external oblique intercostal block with ropivacaine
What this could lead to: If it works, this could offer a better way to manage pain after gallbladder surgery, reducing the need for strong painkillers.
What could go wrong: This is a small, early-stage trial with only 56 people. The nerve block may not provide significant pain relief, and there are rare risks like bleeding or infection from the injection.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LAPAROSCOPIC CHOLECYSTECTOMY POSTOPERATIVE PAIN

Contacts and locations

Locations

Tianmen First People's Hospital

Tianmen, Hubei, 431700, China

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