Which nerve block eases mastectomy pain best? a Head-to-Head trial

NCT ID NCT07737132

Not yet recruiting Symptom relief Sponsor: Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey Source: ClinicalTrials.gov ↗

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This trial compares two ultrasound-guided nerve blocks for pain after modified radical mastectomy: the newer serratus posterior superior intercostal plane block (SPSIPB) and the established serratus anterior plane block (SAPB). Seventy women undergoing mastectomy will receive one of the two blocks before surgery. The goal is to see which provides better pain relief, reduces opioid use, and improves recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: two types of ultrasound-guided nerve blocks: serratus posterior superior intercostal plane block (SPSIPB) and serratus anterior plane block (SAPB), each using bupivacaine
What this could lead to: If one block proves superior, it could become the preferred option for managing pain after mastectomy, reducing opioid use and speeding recovery.
What could go wrong: This is a small, single-center trial with 70 patients, so results may not apply broadly. Both blocks are already in use, so the difference may be small.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER POSTOPERATIVE PAIN

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Other studies related to the condition(s) this trial covers.