New drug combo targets Hard-to-Treat breast cancer in early trial

NCT ID NCT06008275

First seen Nov 10, 2025 · Last updated May 23, 2026 · Updated 25 times

Summary

This early-phase trial tests whether combining two drugs, neratinib and ruxolitinib, is safe and can shrink tumors in people with metastatic triple-negative breast cancer that has come back in the chest wall after chemotherapy. About 20 women aged 18 or older will take both pills daily. The main goal is to see how many patients have a complete or partial response, and how long that response lasts.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baylor University Medical Center, Baylor Charles A Sammons Cancer Center

    RECRUITING

    Dallas, Texas, 75246, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.