Bile duct cancer trial halted after just one patient

NCT ID NCT06739252

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase II trial tested a combination of chemotherapy infused directly into the liver (HAIC) plus two immunotherapy drugs (atezolizumab and bevacizumab) given before and after surgery for high-risk bile duct cancer. The goal was to see if this approach could shrink tumors and improve survival. However, the study was terminated early after enrolling only one participant, so no meaningful conclusions can be drawn.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
gemcitabine, oxaliplatin, 5-fluorouracil, atezolizumab, bevacizumab, capecitabine, tegafur
What this could lead to
If successful, this approach could improve surgical outcomes and reduce recurrence for patients with high-risk bile duct cancer.
What could go wrong
The trial was terminated early with only 1 participant, so results are not reliable. The combination also carries risks like immune-related side effects and liver toxicity.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Peing University Cancer Hospital

    Beijing, Beijing Municipality, 100142, China

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