Could a pill boost brain recovery after stroke? new trial begins

NCT ID NCT06987643

Ongoing Disease control Sponsor: EIP Pharma Inc Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 09, 2026 · Updated 2 times

Summary

This study tests whether a drug called neflamapimod can improve recovery of movement and thinking after a moderate to severe ischemic stroke. About 90 adults aged 45 and older will receive either the drug or a placebo for 12 weeks. The goal is to see if the drug helps reduce disability and improve daily function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: neflamapimod (a p38 alpha kinase inhibitor)
What this could lead to: If it works, this could point toward a new treatment to improve physical and mental recovery after a moderate to severe stroke.
What could go wrong: This is an early proof-of-concept trial with only 90 people. It may fail to show benefit, and the drug's effects on stroke recovery are not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ISCHAEMIC STROKE MODERATE TO SEVERE ACUTE ISCHAEMIC STROKE

Contacts and locations

Locations

Alfred Hospital

Melbourne, Victoria, Australia
Austin Hospital

Heidelberg, Victoria, Australia
Box Hill Hospital

Box Hill, Victoria, Australia
Campbelltown Hospital

Campbelltown, New South Wales, Australia
Gold Coast University Hospital

Southport, Queensland, Australia
Liverpool Hospital

Liverpool, New South Wales, Australia
Royal Brisbane and Women's Hospital

Brisbane, Queensland, Australia
Royal Melbourne Hospital

Melbourne, Victoria, Australia
Sunshine Coast University Hospital

Birtinya, Queensland, Australia
Western Health- Sunshine Hospital

St Albans, Victoria, Australia

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