Less invasive needle treatment could rival surgery for liver tumors

NCT ID NCT05129787

Ongoing Disease control Sponsor: Oslo University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two treatments for colorectal cancer that has spread to the liver: surgical removal of tumors versus a less invasive needle ablation procedure guided by 3D imaging. 230 patients are randomly assigned to one of the two treatments. The goal is to see if ablation works as well as surgery in controlling tumor growth and improving survival.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Thermal ablation (needle ablation with 3D verification) and surgical resection
What this could lead to: If successful, this could show that needle ablation is as effective as surgery for treating liver metastases, offering a less invasive option with faster recovery.
What could go wrong: This is a single-center trial with 230 participants, and results may not apply to all patients. Ablation may have higher local recurrence rates than surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colorectal cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL CANCER METASTATIC

Contacts and locations

Locations

Oslo University Hospital, Department of Gastrointestinal surgery, The National Hospital

Oslo, 0424, Norway

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