New ALS drug trial hopes to slow nerve damage
NCT ID NCT07369076
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests an experimental drug called NB-4746 in 80 people with ALS. The goal is to see if it is safe, how it moves through the body, and whether it can reduce a marker of nerve damage (NfL) in the blood. Participants are randomly assigned to receive either NB-4746 or a placebo for up to 12 weeks, with an option to continue treatment for up to a year.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Calvery Health care Bethlehem
RECRUITINGCaulfield South, Victoria, 3162, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Concord Repatriation General Hospital
RECRUITINGConcord, New South Wales, 2139, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Flinders Medical Centre
RECRUITINGBedford Park, South Australia, 5042, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Genge Partners
RECRUITINGMontreal, Quebec, H4A 3T2, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Neuroscience Research Australia
RECRUITINGRandwick, New South Wales, 2031, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Perron Institute
RECRUITINGNedlands, Western Australia, 6009, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Royal Brisbane and Women's Hospital
RECRUITINGBrisbane, Queensland, 4029, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Stan Cassidy Center for Rehabilitation
RECRUITINGFredericton, New Brunswick, E3B 0C7, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••