New ALS drug trial aims to slow nerve damage
NCT ID NCT07369076
First seen Feb 01, 2026 · Last updated May 16, 2026 · Updated 14 times
Summary
This trial tests an experimental drug called NB-4746 in 80 people with ALS. The study has two parts: first, a short safety check with low or high doses, then a longer 12-week comparison against a placebo. Researchers will monitor side effects, how the drug moves through the body, and changes in a blood marker of nerve damage. After the main study, participants can choose to continue treatment for up to a year.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Concord Repatriation General Hospital
RECRUITINGConcord, New South Wales, 2139, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Flinders Medical Centre
RECRUITINGBedford Park, South Australia, 5042, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Genge Partners
RECRUITINGMontreal, Quebec, H4A 3T2, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Neuroscience Research Australia
RECRUITINGRandwick, New South Wales, 2031, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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