10-Year study tracks hidden DNA changes that raise risk of blood cancer and heart disease

NCT ID NCT04102423

First seen Oct 31, 2025 · Last updated May 10, 2026 · Updated 25 times

Summary

This study follows 306 adults with certain DNA changes in their blood cells (called CHIP or CCUS) to see how these changes affect health over time. Researchers will track whether participants develop blood cancers, heart disease, or other conditions. Participants give blood and urine samples, have heart and lung tests, and return for yearly checkups for up to 10 years.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.