Your Child's nose bacteria may boost flu shot power

NCT ID NCT06609811

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how bacteria living in the nose and gut influence the immune response to a nasal flu vaccine in 201 children aged 6 to 17. Half got the vaccine right away, half waited 28 days. Researchers collected samples before and after vaccination to measure antibodies and bacterial changes. The goal was to understand if these natural microbes help or hinder vaccine effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Intranasal Influenza Live Attenuated Vaccine

What this could lead to

If successful, this could help design better flu vaccines by understanding how natural bacteria in the nose and gut influence immune protection.

What could go wrong

This is a completed Phase 4 study focused on observation, not testing a new treatment. Results may not lead to immediate changes in vaccine recommendations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

influenza prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Haizhou District Center for Disease Control and Prevention

    Lianyungang, Jiangsu, China