Your Child's nose bacteria may boost flu shot power

NCT ID NCT06609811

Completed Knowledge-focused Sponsor: Jiangsu Province Centers for Disease Control and Prevention Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how bacteria living in the nose and gut influence the immune response to a nasal flu vaccine in 201 children aged 6 to 17. Half got the vaccine right away, half waited 28 days. Researchers collected samples before and after vaccination to measure antibodies and bacterial changes. The goal was to understand if these natural microbes help or hinder vaccine effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Intranasal Influenza Live Attenuated Vaccine
What this could lead to: If successful, this could help design better flu vaccines by understanding how natural bacteria in the nose and gut influence immune protection.
What could go wrong: This is a completed Phase 4 study focused on observation, not testing a new treatment. Results may not lead to immediate changes in vaccine recommendations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for INFLUENZA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

influenza prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFLUENZA

Contacts and locations

Locations

Haizhou District Center for Disease Control and Prevention

Lianyungang, Jiangsu, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.