Topical gel could ease rib fracture pain in the ER
NCT ID NCT07706036
First seen Jul 15, 2026 · Last updated Jul 21, 2026 · Updated 3 times
Summary
This trial tests whether adding a topical gel containing naproxen and lidocaine to standard intravenous pain medication improves pain relief for adults with isolated rib fractures from blunt chest trauma. Participants receive either the standard IV painkiller alone or the IV painkiller plus a one-time application of the gel over the fractured area. Pain levels are tracked over the first hour, and the need for extra rescue pain medication is compared between the two groups.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a topical gel containing 10% naproxen and 5% lidocaine, applied once over the fractured rib area as an add-on to intravenous dexketoprofen
- What this could lead to
- If effective, this gel could offer a simple, non-invasive way to improve pain control for rib fracture patients in the emergency room, potentially reducing the need for stronger rescue painkillers.
- What could go wrong
- This is a small, early-stage trial with only 110 participants. The gel is applied just once, so its benefit may be limited or not significantly better than standard care alone.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Ankara Bilkent City Hospital; Department of Emergency Medicine
Ankara, Çankaya, 06800, Turkey (Türkiye)
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