New combo could cut morphine use after hip surgery
NCT ID NCT06577155
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding nalbuphine to the standard spinal anesthetic levobupivacaine helps control pain after total hip replacement. Sixty adults were split into two groups: one received levobupivacaine alone, the other received levobupivacaine plus nalbuphine. Researchers measured how much morphine patients needed in the first 24 hours, along with pain scores and side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- nalbuphine
- What this could lead to
- If it works, this could offer better pain relief and less need for morphine after hip replacement surgery.
- What could go wrong
- This is a small, early-phase study with only 60 patients, so results may not apply to everyone. Adding nalbuphine may also cause side effects like dizziness or nausea.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Asklepieion Hospital of Voula
Athens, Ελλάδα (+30), 16675, Greece
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