New combo could cut morphine use after hip surgery
NCT ID NCT06577155
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding nalbuphine to the standard spinal anesthetic levobupivacaine helps control pain after total hip replacement. Sixty adults were split into two groups: one received levobupivacaine alone, the other received levobupivacaine plus nalbuphine. Researchers measured how much morphine patients needed in the first 24 hours, along with pain scores and side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nalbuphine
What this could lead to
If it works, this could offer better pain relief and less need for morphine after hip replacement surgery.
What could go wrong
This is a small, early-phase study with only 60 patients, so results may not apply to everyone. Adding nalbuphine may also cause side effects like dizziness or nausea.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Asklepieion Hospital of Voula
Athens, Ελλάδα (+30), 16675, Greece