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New antibody-chemo combo shows promise against tough breast cancer

NCT ID NCT05181462

Completed Disease control Sponsor: Cantargia AB Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new drug called nadunolimab, which blocks a protein that helps cancer grow, combined with standard chemotherapy for people with advanced triple-negative breast cancer. The trial had two parts: first to find a safe dose, then to see if the combination shrinks tumors better than chemo alone. 117 participants were enrolled, and the goal was to improve treatment options for this aggressive cancer.

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Conditions

The condition(s) this trial relates to.

triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TRIPLE NEGATIVE BREAST CANCER

Contacts and locations

Locations

  • Clínica Universidad de Navarra

    Pamplona, Navarre, 31008, Spain

  • Complejo Hospitalario Universitario A Coruña

    A Coruña, Galicia, 15006, Spain

  • Complejo Hospitalario Universitario de Albacete

    Albacete, Castille-La Mancha, 02006, Spain

  • Complejo Hospitalario de Jaén

    Jaén, Andalusia, 23007, Spain

  • Fundación Instituto Valenciano de Oncología

    Valencia, Valencia, 46009, Spain

  • Hospital Clinic de Barcelona

    Barcelona, Catalonia, 08036, Spain

  • Hospital Clínico San Carlos

    Madrid, Madrid, 28040, Spain

  • Hospital Clínico Universitario Lozano Blesa

    Zaragoza, Aragon, 50009, Spain

  • Hospital Materno Infantil de Gran Canaria

    Las Palmas de Gran Canaria, Las Palmas, 35016, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, Madrid, 28041, Spain

  • Hospital Universitario Arnau de Vilanova Lleida

    Lleida, Catalonia, 25198, Spain

  • Hospital Universitario Clinico San Cecilio

    Granada, Andalusia, 18016, Spain

  • Hospital Universitario Gregorio Marañón

    Madrid, Madrid, 28007, Spain

  • Hospital Universitario Lucus Augusti

    Lugo, Galicia, 27003, Spain

  • Hospital Universitario San Juan de Alicante

    Alicante, Valencia, 03550, Spain

  • Hospital Universitario Virgen De La Victoria

    Málaga, Andalusia, 29010, Spain

  • Hospital Universitario Virgen Del Rocío

    Seville, Andalusia, 41013, Spain

  • Hospital Universitario Virgen Macarena

    Seville, Andalusia, 41009, Spain

  • Hospital Universitario Virgen de las Nieves

    Granada, Andalusia, 18014, Spain

  • Hospital Universitario de Toledo

    Toledo, Castille-La Mancha, 45007, Spain

  • Hospital del Mar

    Barcelona, Catalonia, 08003, Spain

  • ICO Institut Catalá d'Oncologia de L´Hospitalet

    Hospitalet de Llobregat, Barcelona, Catalonia, 08908, Spain

  • Onkologikoa

    Donostia / San Sebastian, Basque Country, 20014, Spain

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