Could a common antioxidant ease early psychosis symptoms?

NCT ID NCT05142735

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether N-acetylcysteine (NAC), a safe antioxidant supplement, can reduce early psychosis-like symptoms in 90 people at clinical high risk for schizophrenia. Participants take NAC for 8 weeks, and researchers measure changes in symptoms and brain activity. The goal is to find a well-tolerated treatment option for those with early warning signs.

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Conditions

The condition(s) this trial relates to.

Psychotic Disorders Schizophrenia schizotypal personality disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre for Addiction and Mental Health

    RECRUITING

    Toronto, Ontario, M5T 1R8, Canada

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