Misted chemotherapy shows promise for advanced stomach cancer in early trial
NCT ID NCT06675136
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial is testing a new method of delivering chemotherapy directly into the abdomen as a fine mist under pressure (PIPAC) for people with stomach cancer that has spread to the lining of the belly. The study combines this misted chemotherapy (nab-paclitaxel) with standard second-line drugs given through a vein. The main goals are to find the safest dose and see if the combination is tolerable. About 30 participants who have already tried one line of treatment will be enrolled.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nab-paclitaxel (a form of chemotherapy) given as a pressurized mist into the abdomen, plus paclitaxel and ramucirumab (another chemotherapy and an antibody) given through a vein
What this could lead to
If this works, it could offer a new treatment option for stomach cancer that has spread to the lining of the belly, potentially slowing the disease.
What could go wrong
This is a very early (Phase 1) trial with only 30 people, so the main goal is safety, not effectiveness. The combination may cause serious side effects or not work better than existing treatments.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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City of Hope Medical Center
RECRUITINGDuarte, California, 91010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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