New hope for aggressive breast cancer: two chemo cocktails face off in clinical trial
NCT ID NCT04159142
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This Phase 2 trial is testing two different chemotherapy combinations in 414 women with advanced triple-negative breast cancer (TNBC), a fast-growing type that lacks common treatment targets. One group gets nab-paclitaxel plus carboplatin, the other gets nab-paclitaxel plus capecitabine. The goal is to see which combo works better at slowing the cancer's growth and improving survival, while monitoring side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- nab-paclitaxel plus carboplatin or capecitabine
- What this could lead to
- If successful, this could identify a more effective chemotherapy combination for advanced triple-negative breast cancer, potentially improving survival and delaying disease progression.
- What could go wrong
- This is a Phase 2 trial, so results are still early. Chemotherapy can cause significant side effects, and the benefit may be modest or not confirmed in larger studies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The Fourth Hospital of Hebei Medical University
RECRUITINGShijiazhuang, Hebei, 050011, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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