Tooth repair trial tests antioxidant boost for root growth

NCT ID NCT03451435

First seen Jan 21, 2026 · Last updated May 07, 2026 · Updated 13 times

Summary

This early-stage study tested whether adding N-acetyl cysteine (NAC) to a standard dental procedure helps stem cells in the tooth grow roots to full maturity. The procedure involves cleaning the tooth and inducing bleeding to activate stem cells. The trial planned 14–18 healthy children and teens with immature, dead teeth, but was terminated early with only 7 participants. Results are limited.

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Contacts and locations

Locations

  • University of California, Los Angeles Dept of Graduate Endodontics

    Los Angeles, California, 90095, United States

Conditions

Explore the condition pages connected to this study.