Could common antioxidants help thalassemia patients?
NCT ID NCT07157722
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This Phase 3 trial tests whether two antioxidant supplements, N-acetyl cysteine and alpha-lipoic acid, can improve blood vessel health and reduce oxidative stress in adults with beta thalassemia. Sixty-six participants will take one of the supplements or a placebo alongside their usual treatment for 12 weeks. The study focuses on changes in artery thickness and blood markers of inflammation and oxidative damage.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
N-acetyl cysteine and alpha-lipoic acid
What this could lead to
If it works, this could point toward a simple, low-cost way to reduce heart-related complications in people with beta thalassemia.
What could go wrong
This is a small, early-stage trial with only 66 participants, and the outcomes are mainly lab markers, not direct health benefits. The supplements may not produce meaningful clinical improvements.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Faculty of Pharmacy - Tanta University
Tanta, 31511, Egypt
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••