New heart valve registry aims to improve aortic stenosis treatment

NCT ID NCT06818435

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This registry will follow 150 people in Portugal who receive the Myval heart valve through a minimally invasive procedure called TAVI. The goal is to see how safe and effective the valve is for treating severe aortic stenosis. Researchers will track complications like death, stroke, kidney injury, and bleeding over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Myval THV series (a replacement heart valve implanted via a catheter)

What this could lead to

If successful, this registry could confirm that the Myval valve is a safe and effective option for treating severe aortic stenosis without open-heart surgery.

What could go wrong

This is an observational registry, not a controlled trial, so results may be less definitive. Risks include serious complications like stroke, bleeding, or need for a pacemaker.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Unidade Local de Saúde Alentejo Central E.P.E. - Hospital Espírito Santo

    RECRUITING

    Evora, 7000-811, Portugal

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Unidade Local de Saúde de Coimbra

    RECRUITING

    Coimbra, 3004-561, Portugal

    Contact Email: •••••@•••••

  • Unidade Local de Saúde de Santa Maria, E.P.E. - Hospital de Santa Maria

    RECRUITING

    Lisbon, 1649-035, Portugal

    Contact Email: •••••@•••••

  • Unidade Local de Saúde de São José E.P.E. - Hospital Santa Marta

    NOT_YET_RECRUITING

    Lisbon, 1169-024, Portugal

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Unidade Local de Saúde do Lisboa Ocidental E.P.E. - Hospital Santa Cruz

    RECRUITING

    Carnaxide, 2790-134, Portugal

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Unidade Local de São João E.P.E.

    NOT_YET_RECRUITING

    Porto, 4200-319, Portugal

    Contact Phone: •••-•••-•••• Email: •••••@•••••