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Heart MRI may unlock secrets of thick heart muscle diseases

NCT ID NCT07382128

Recruiting now Knowledge-focused Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study uses advanced heart MRI scans to look at blood flow patterns in people with different types of hypertrophic cardiomyopathy (thick heart muscle), including rare forms like Anderson-Fabry disease and cardiac amyloidosis. Researchers will also study first-degree relatives and genetic carriers. The goal is to find unique blood flow 'fingerprints' for each condition, which could help doctors tell them apart more easily and predict risks like scarring or irregular heartbeats.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better distinguish between different types of hypertrophic cardiomyopathy using a non-invasive MRI scan, leading to more accurate diagnoses and personalized care.
What could go wrong
This is an observational study, not a treatment trial, so it will not directly benefit participants. The findings may not lead to immediate changes in clinical practice.

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Conditions

The condition(s) this trial relates to.

Amyloid Neuropathies, Familial Fabry disease hypertrophic cardiomyopathy restrictive cardiomyopathy wild type ATTR amyloidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AMYLOID CARDIOMYOPATHY ANDERSON FABRY DISEASE CARDIAC MAGNETIC RESONANCE IMAGING HCM - HYPERTROPHIC CARDIOMYOPATHY

Contacts and locations

Locations

  • IRCCS Azienda Ospedaliero-Universitaria di Bologna

    RECRUITING

    Bologna, BO, 40124, Italy

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