Heart drug trial halted early: MYK-224 studied for thick heart muscle

NCT ID NCT05556343

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an experimental drug called MYK-224 in 18 adults with a type of heart disease that makes the heart muscle too thick and blocks blood flow. The goal was to see if the drug is safe and helps reduce symptoms. The trial was stopped early, so results are limited.

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Conditions

The condition(s) this trial relates to.

hypertrophic cardiomyopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Local Institution - 0001

    Kansas City, Kansas, 66103-2937, United States

  • Local Institution - 0002

    El Palmar, MU, 30120, Spain

  • Local Institution - 0003

    Valencia, V, 46026, Spain

  • Local Institution - 0005

    Florence, FI, 50134, Italy

  • Local Institution - 0006

    Salt Lake City, Utah, 84132, United States

  • Local Institution - 0008

    Málaga, MA, 29010, Spain

  • Local Institution - 0009

    A Coruña, 15006, Spain

  • Local Institution - 0010

    Majadahonda, 28035, Spain

  • Local Institution - 0011

    Katowice, Silesian Voivodeship, 40-555, Poland

  • Local Institution - 0013

    Durham, North Carolina, 27710, United States

  • Local Institution - 0014

    Los Angeles, California, 90048, United States

  • Local Institution - 0015

    Cleveland, Ohio, 44195-0001, United States

  • Local Institution - 0016

    San Francisco, California, 94158-2156, United States

  • Local Institution - 0021

    Nashville, Tennessee, 37205-2202, United States

  • Local Institution - 0022

    Granada, GR, 18014, Spain

  • Local Institution - 0023

    Barcelona, 08036, Spain

  • Local Institution - 0024

    Portland, Oregon, 97239-3011, United States

  • Local Institution - 0025

    San Antonio, Texas, 78229-3900, United States

  • Local Institution - 0026

    La Jolla, California, 92037, United States

  • Local Institution - 0027

    Bologna, BO, 40138, Italy

  • Local Institution - 0028

    Alicante, A, 03010, Spain

  • Local Institution - 0029

    Milan, 20138, Italy

  • Local Institution - 0030

    Wroclaw, 54-049, Poland

  • Local Institution - 0031

    Cincinnati, Ohio, 45267, United States

  • Local Institution - 0032

    New York, New York, 10032-3802, United States