Fibroid surgery Follow-Up drug trial pulled before it began

NCT ID NCT05538689

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aimed to see if taking Myfembree (a combination pill) daily after fibroid removal surgery could delay the return of fibroids and improve quality of life. It was designed for premenopausal women with uterine fibroids who had surgery. However, the trial was withdrawn before any participants were enrolled, so no data were collected.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Myfembree (relugolix, estradiol, norethindrone acetate)

What this could lead to

If it had worked, this could point toward a way to delay fibroid regrowth and reduce the need for repeat surgery after myomectomy.

What could go wrong

The trial was withdrawn before enrolling anyone, so no results are available. Even if conducted, it was a small early-phase study, and benefits may not have been confirmed.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

leiomyoma Menorrhagia Metrorrhagia Pelvic Pain uterine corpus leiomyoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Chicago DCAM

    Chicago, Illinois, 60637, United States

  • University of Chicago Flossmoor

    Flossmoor, Illinois, 60422, United States

  • University of Chicago Orland Park

    Orland Park, Illinois, 60462, United States

  • University of Chicago River East

    Chicago, Illinois, 60611, United States

  • University of Chicago Schererville

    Schererville, Indiana, 46375, United States

  • University of Chicago South Loop

    Chicago, Illinois, 60607, United States