Music during surgery may tame stress and inflammation

NCT ID NCT06166186

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether playing music through headphones during liver donation surgery could reduce the body's stress and inflammation response. 61 adult liver donors were randomly assigned to hear music or no music during their operation. Researchers measured inflammatory markers like interleukin-6 and TNF-alpha in blood samples taken before and after surgery to see if music made a difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
music
What this could lead to
If it works, this could point toward a simple, drug-free way to reduce stress and inflammation during major surgery.
What could go wrong
This is a small, completed study with only 61 participants. The results may not apply to all surgeries or patients, and the effect of music on inflammation is still uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Fractures, Stress

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Istinye University Hospital

    Istanbul, Turkey (Türkiye)

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