Muscle relaxant dose may hold key to better breathing tube alternative
NCT ID NCT07828977
First seen Sep 18, 2026 · Last updated Sep 18, 2026
Summary
Researchers are studying whether the amount of a muscle relaxant called rocuronium affects how well a laryngeal mask airway works during general anesthesia. The laryngeal mask is a soft tube placed in the throat to help patients breathe, an alternative to a traditional breathing tube. In this trial, 96 adults having short elective surgeries are randomly assigned to receive no rocuronium or one of two doses before the mask is placed. The team measures how well the mask seals against the airway and tracks insertion success, breathing measures, and any airway complications.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- rocuronium, a muscle relaxant given before placing a breathing tube alternative called a laryngeal mask
- What this could lead to
- If it works, this could help anesthesiologists choose the right dose of muscle relaxant to make laryngeal mask insertion easier and ventilation more reliable during surgery.
- What could go wrong
- This is a small, single-center study of 96 people having short elective surgeries, so the results may not apply to everyone or to longer or more complex operations. Muscle relaxants can cause prolonged weakness or allergic reactions, though these are uncommon.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 96 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Scheduled for elective surgery under general anesthesia with a video * laryngeal mask airway * Expected duration of surgery less than 3 hours * Surgery performed in the supine position * Provision of written informed consent Exclusion Criteria: * Symptoms or signs of upper respiratory tract infection * Increased risk of pulmonary aspiration * Anticipated difficult airway * Limited mouth opening (\<3 cm) * Limited head or neck movement * Mallampati class IV * Body mass index ≥35 kg/m²
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
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