New cream aims to cut opioid use after knee surgery
NCT ID NCT06202989
First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times
Summary
This study tests whether a prescription pain cream called Multiprofen-CC™ can help control pain and reduce the need for opioid painkillers after total knee replacement. About 288 adults having knee surgery will use either the cream or a placebo along with standard pain care. The goal is to see if the cream improves pain scores and satisfaction while lowering opioid use.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Locations
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St. Joseph's Healthcare Hamilton
Hamilton, Ontario, L8N 4A6, Canada