New cream aims to cut opioid use after knee replacement
Symptom relief
Recruiting now
This study tests whether a prescription topical cream called Multiprofen-CC™ can help control pain and reduce the need for opioid painkillers after total knee replacement surgery. About 288 adults having knee replacement will use either the cream or a placebo along with standard …
Phase: PHASE3 • Sponsor: KAZM Pharmaceuticals Inc. • Aim: Symptom relief
Last updated May 17, 2026 11:34 UTC