New hope for elderly myeloma patients: easier treatment without transplant

NCT ID NCT03993912

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 22 times

Summary

This study tests whether adding daratumumab (given as a shot under the skin) to the standard drug lenalidomide helps frail older adults with newly diagnosed multiple myeloma live longer without their cancer getting worse. About 294 participants aged 65 and older who cannot have a stem cell transplant will receive either the new combo or standard treatment. The goal is to find a more effective and less toxic option for this vulnerable group.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Centre Hospitalier Saint-Malo

    St-Malo, France

  • Centre Hospitalier de Perigueux

    Périgueux, France

  • Centre Hospitalier de Saint Quentin

    Saint-Quentin, France

  • Ch Blois Simone Veil

    Blois, France

  • Ch Chartres Louis Pasteur-Le Coudray

    Le Coudray, France

  • Ch Fleyriat

    Bourg-en-Bresse, France

  • Chi Mont de Marsan Et Pays Des Sources

    Mont-de-Marsan, France

  • Chru Brest Site Hopital Morvan

    Brest, France

  • Chru Jean Minjoz

    Besançon, France

  • Chru Rennes Site Pontchaillou

    Rennes, France

  • Chu Dijon Bourgogne

    Dijon, France

  • Chu Montpellier

    Montpellier, France

  • Chu de Caen Normandie

    Caen, France

  • Chu de Grenoble

    Grenoble, France

  • Chu de Nantes Site Hotel Dieu Hme

    Nantes, France

  • Chu de Nice Hopital de L'Archet

    Nice, France

  • Chu de Tours

    Tours, France

  • Gpe Hospitalier La Rochelle-Re-Aunis

    La Rochelle, France

  • Hopital Haut-Leveque - Chu

    Pessac, 33604, France

  • Hopital Prive Sevigne - Cesson

    Cesson-Sévigné, France

  • Hôpital Claude Huriez, CHU

    Lille, France

  • Institut Paoli Calmettes

    Marseille, France

  • Oncopole Chu Toulouse

    Toulouse, France

Conditions

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